Cellular consequences to severe DSB repair deficiency

Cancer cells are incentivized to modulate their DNA repair activities in order to adapt and survive. We are interested in unraveling these dependencies. Gif adapted from Ted-Ed

Cancer cells are incentivized to modulate their DNA repair activities in order to adapt and survive. We are interested in unraveling these dependencies. Gif adapted from Ted-Ed

We will leverage the HTGTS platform to assess phenotypic responses of DSB repair genes to various “treatments”.

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Modulating DSB repair